3-Chloro-6-methylbenzothiophene-2-carboxylic Acid CAS 34576-96-0
| CAS No. | 34576-96-0 |
| Molecular Formula | C10H7ClO2S |
| Molecular Weight | 226.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 3-Chloro-6-methylbenzothiophene-2-carboxylic Acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 226.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3-Chloro-6-methylbenzothiophene-2-carboxylic Acid (CAS 34576-96-0) is a high-purity analytical reference standard with the molecular formula C10H7ClO2S and a molecular weight of 226.68 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7ClO2S |
| Molecular Weight | 226.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-((4-Chloro-1H-pyrazol-1-yl)methyl)thiophene-2-carbaldehyde (CAS 1006493-41-9)
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- 7-Chloro-1-cyclopropyl-6-fluoro-1,2,3,4-tetrahydroquinoxaline (CAS 1315469-43-2)
- 3-Chloro-7-methoxybenzo[b]thiophene-2-carbaldehyde (CAS 1315550-49-2)
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- n-(6-Chloro-1,3-benzothiazol-2-yl)acetamide (CAS 16628-24-3)
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Recommended Standards
- 3-Chloro-4-(1,3-thiazol-2-yloxy)aniline (CAS 871021-06-6)
- 4-Chloro-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidine (CAS 243968-08-3)
- 3-Chloro-1-benzothiophene-2-carbohydrazide (CAS 62524-21-4)
- 4-Chloro-6-(oxetan-3-yl)thieno[3,2-d]pyrimidine (CAS 2227205-57-2)
- 1-(3-(Trifluoromethyl)-1H-pyrazol-1-yl)-3-((4-(trifluoromethyl)benzyl)amino)propan-2-ol (CAS 680594-01-8)
- 2-[(E)-2-(2,4-Dimethoxyphenyl)ethenyl]-1-methylpyridin-1-ium iodide (CAS 300347-38-0)
- 2,2'-(1,4-Phenylene)bis(quinoline-4-carboxylic acid) (CAS 314022-35-0)
- 2-Chloro-N-ethyl-N-(m-tolyl)acetamide (CAS 86491-92-1)
- Formoterol Impurity 71 (CAS 71250-20-9)
- (S)-3-Phenylpiperazin-2-one (CAS 1240585-52-7)
- (R)-3-(Phenylsulfonyl)pyrrolidine (CAS 1268521-39-6)
- Ethyl (2E)-3-(1H-imidazol-4-yl)prop-2-enoate (CAS 27538-35-8)
- 2-Bromo-4-chloro-6-methoxyaniline (CAS 1261895-84-4)
- Liraglutide(14-22)TFA Salt (CAS CATO-C4X-199212)
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