4-((4-Chlorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde CAS 345983-01-9
| CAS No. | 345983-01-9 |
| Molecular Formula | C15H12ClIO3 |
| Molecular Weight | 402.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-((4-Chlorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde.
4-((4-Chlorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde (CAS 345983-01-9) is a high-purity analytical reference standard with the molecular formula C15H12ClIO3 and a molecular weight of 402.61 g/mol.
The molecular framework of 4-((4-Chlorobenzyl)oxy)-3-iodo-5-methoxybenzaldehyde (C15H12ClIO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12ClIO3 |
| Molecular Weight | 402.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/I-containing |
Related Chlorobenzyl Standards
- 4-((4-Chlorobenzyl)oxy)-3-iodobenzohydrazide (CAS 1706463-99-1)
- 4-[(2-chlorobenzyl)oxy]-3-iodo-5-methoxybenzaldehyde (CAS 345985-63-9)
- N-(2-Chlorobenzyl)-2-(8-morpholino-3-oxo-[1,2,4]triazolo[4,3-a]pyrazin-2(3H)-yl)acetamide (CAS 1251569-14-8)
- (2-((2-Chlorobenzyl)oxy)phenyl)(1-(p-tolyl)-1H-pyrazol-4-yl)methanone (CAS 956779-42-3)
- (3-(2-((4-Chlorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)(p-tolyl)methanone (CAS 477713-37-4)
- 3-((4-Chlorobenzyl)sulfonyl)-N-(4-chlorophenyl)-2-hydroxy-2-methylpropanamide (CAS 338424-18-3)
- 1-(4-Chlorobenzyl)-4,6-dimethyl-3-(m-tolylsulfonyl)pyridin-2(1H)-one (CAS 338398-02-0)
- N1-(2-Chlorobenzyl)-N2-(2-(2-phenylmorpholino)ethyl)oxalamide (CAS 954004-29-6)
Recommended Standards
- 1,3-Propanediol, 2,2-bis(hydroxymethyl)-, homopolymer, isooctadecanoate (CAS 71010-66-7)
- 1-(4-Chlorophenyl)-2-[(5-iodo-2,6-dimethylpyrimidin-4-yl)oxy]ethan-1-one (CAS 477871-93-5)
- Dihydrotestosterone Heptanoate (CAS 33776-88-4)
- 1-(3-Chloro-2-hydroxy-4-((4-iodobenzyl)oxy)phenyl)ethanone (CAS 888968-75-0)
- 2-Chloro-5-isopropylpyridin-4-amine (CAS 1381935-97-2)
- (R)-2-Cyclopropyl-1,2,3,4-tetrahydroquinoxaline (CAS 1821777-14-3)
- (R)-2-(3-hydroxypiperidin-1-yl)acetic acid (CAS 1354002-75-7)
- 6-Chloro-N-(thiazol-2-yl)nicotinamide (CAS 761421-09-4)
- 4-Bromobenzofuran-2-carbaldehyde (CAS 177735-24-9)
- N-(4-methoxybenzyl)-3-nitroaniline (CAS 305851-22-3)
- 1-Butyl-3,5-dimethyl-1H-pyrazole-4-carbaldehyde (CAS 957483-76-0)
- 1-((2-Methoxyphenyl)amino)-3-(naphthalen-1-yloxy)propan-2-ol (CAS 450363-95-8)
- H-Val-Leu-Lys-pNA . 2 HCl (L-1450.0050) (CAS 201807-16-1)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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