1-(2-Chlorophenyl)prop-2-yn-1-one CAS 3463-33-0
| CAS No. | 3463-33-0 |
| Molecular Formula | C9H5ClO |
| Molecular Weight | 164.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Chlorophenyl)prop-2-yn-1-one.
CATO supplies 1-(2-Chlorophenyl)prop-2-yn-1-one (CAS 3463-33-0), a certified reference material (molecular formula C9H5ClO, MW 164.59 g/mol) for analytical method development and quality control.
Based on its molecular formula C9H5ClO, 1-(2-Chlorophenyl)prop-2-yn-1-one contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 164.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClO |
| Molecular Weight | 164.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 1-(3-Chlorophenyl)prop-2-yn-1-one (CAS 33899-25-1)
- 1-(4-Chlorophenyl)prop-2-yn-1-one (CAS 22959-34-8)
- (2-Chlorophenyl)(hydroxy)(vinyl)borane (CAS 871817-23-1)
- (E)-3-(3-Chlorophenyl)acrylonitrile (CAS 14378-03-1)
- 3-(4-Chlorophenyl)prop-2-enenitrile (CAS 14378-04-2)
- (2E)-3-(4-chlorophenyl)acrylonitrile (CAS 28446-72-2)
- (E)-3-(2-Chlorophenyl)acrylonitrile (CAS 51220-00-9)
- 1-(3-Chlorophenyl)ethyl isocyanide (CAS 1041635-04-4)
Recommended Standards
- (2-Tetrahydrofuranyl)methyl Chloroformate (CAS 64661-06-9)
- 3-Chloro-4-ethynylbenzaldehyde (CAS 1856380-11-4)
- 2-Chloro-4-ethynylbenzaldehyde (CAS 1849215-25-3)
- 1,7-naphthyridine, 2-chloro- (CAS 35192-05-3)
- ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate (CAS 1035404-19-3)
- 4-Nitrobenzoxazole-2(3H)-thione (CAS 101495-34-5)
- Ethyl 4-(2-aminoethyl)piperidine-1-carboxylate (CAS 106244-90-0)
- 2-[2-(3-Fluorophenyl)ethoxy]acetic acid (CAS 953786-95-3)
- 4-Amino-N-cyclopentyl-1,2,5-oxadiazole-3-carboxamide (CAS 924844-44-0)
- 3-((Diethylamino)methyl)piperidin-3-ol dihydrochloride (CAS 2306262-28-0)
- (E)-{1-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)pyridin-2-yl]ethylidene}amino N,N-dimethylcarbamate (CAS 900019-62-7)
- Glimepiride Impurity 20 (CAS 607-97-6)
- 3,3-Dimethylbicyclo[2.2.1]heptan-2-one (CAS 13211-15-9)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
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