N-(3-Chloro-4-fluorophenyl)-3-methylbenzamide CAS 346720-16-9
| CAS No. | 346720-16-9 |
| Molecular Formula | C14H11ClFNO |
| Molecular Weight | 263.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N-(3-Chloro-4-fluorophenyl)-3-methylbenzamide (CAS 346720-16-9), a certified reference material (molecular formula C14H11ClFNO, MW 263.69 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(3-Chloro-4-fluorophenyl)-3-methylbenzamide is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 263.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11ClFNO |
| Molecular Weight | 263.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 4-Chloro-N-(2-fluoro-4-methylphenyl)benzamide (CAS 1017108-34-7)
- 3-Chloro-N-(4-fluoro-3-methylphenyl)benzamide (CAS 1026455-53-7)
- 3-Chloro-N-(2-fluoro-4-methylphenyl)benzamide (CAS 1037953-69-7)
- 2-Chloro-N-(2-fluorophenyl)-2-phenylacetamide (CAS 1094448-02-8)
- 7-Chloro-3-(4-fluorophenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1173183-91-9)
- 4-Chloro-N-(2-fluoro-5-methylphenyl)benzamide (CAS 1180086-40-1)
- (R)-2-(3-chloro-5-(trifluoromethyl)phenyl)piperidine (CAS 1212970-07-4)
- (R)-2-(3-chloro-4-(trifluoromethyl)phenyl)piperidine (CAS 1213150-48-1)
Recommended Standards
- N-(3-chloro-2-methylphenyl)-4-fluorobenzamide (CAS 331270-53-2)
- N-(3-Chloro-4-fluorophenyl)-4-methylbenzamide (CAS 329938-69-4)
- N-(3-Chloro-2-methylphenyl)-2-fluorobenzamide (CAS 349128-44-5)
- N-(3-Chloro-4-methylphenyl)-2-fluorobenzamide (CAS 331445-10-4)
- 5-Chloro-2-methylbenzo[d]oxazole-6-sulfonyl chloride (CAS 88787-45-5)
- 3-Phenyl-5-(pyridin-2-ylmethylene)-2-selenoxothiazolidin-4-one (CAS 375368-24-4)
- 4-(Hexyloxy)-3-iodobenzoic acid (CAS 1131614-78-2)
- 1-(Methoxymethoxy)-2-nitrobenzene (CAS 25458-47-3)
- Gly-Gly-Tyr-Arg (CAS 70195-20-9(free base))
- Thioctic acid Impurity 96 (CAS CATO-C4X-152696)
- 2-(3-Bromophenyl)-7-methylimidazo[1,2-a]pyridine (CAS 419557-37-2)
- (S)-2-chloro-1-(pyrrolidin-2-yl)ethan-1-one (CAS 38491-75-7)
- 1-(5,6-Dimethylbenzofuran-2-yl)ethan-1-one (CAS 16563-98-7)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
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