1-Propyl-2-pyrrolidinone CAS 3470-99-3
| CAS No. | 3470-99-3 |
| Molecular Formula | C15H18BrN |
| Molecular Weight | 292.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Propyl-2-pyrrolidinone.
1-Propyl-2-pyrrolidinone (CAS 3470-99-3) is a high-purity analytical reference standard with the molecular formula C15H18BrN and a molecular weight of 292.21 g/mol.
The molecular framework of 1-Propyl-2-pyrrolidinone (C15H18BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Propyl-2-pyrrolidinone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H18BrN |
| Molecular Weight | 292.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Propyl Standards
- 2-Pyrrolidinone, 3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-(phenylmethyl)-, (3S)- (CAS 1956436-52-4)
- 2-Pyrrolidinone, 1-(3,4-dichlorophenyl)-4-(hydroxymethyl)- (CAS 133748-10-4)
- 2-PYRROLIDINONE, 4-(2,5-DIMETHOXYPHENYL) (CAS 654633-86-0)
- 2-Pyrrolidinone, 4-(3,4-dimethoxyphenyl)- (CAS 6891-55-0)
- 2-Pyrrolidinone, 1-ethenyloctadecyl-, homopolymer (CAS 63231-83-4)
- 2-PYRROLIDINONE, 4-(2-METHOXYPHENYL) (CAS 1020718-50-6)
- 3-Ethyl-2-pyrrolidinone (CAS 930-92-7)
- 2-PYRROLIDINONE, 4-(3-METHYLPHENYL) (CAS 1019650-80-6)
Recommended Standards
- 1-[1-(2,2,2-Trifluoroacetyl)piperidin-3-yl]-1H-1,2,3-triazole-4-carboxylic acid (CAS 2034576-87-7)
- 3-[[(2,4-Dichlorophenyl)methyl]thio]-1,2,4-thiadiazol-5-amine (CAS 650594-75-5)
- tert-Butyl 3-(bromomethyl)-5-methylpiperidine-1-carboxylate (CAS 1934683-34-7)
- 4-((2-Nitro-4-(trifluoromethyl)phenyl)amino)butanoic acid (CAS 65783-35-9)
- 4,4,4-Trifluoro-3-(4-(trifluoromethyl)phenyl)but-2-enoic acid (CAS 903094-75-7)
- 1-(4-Ethoxyphenyl)-2-(methylamino)ethan-1-ol (CAS 1017480-59-9)
- 2-Amino-3-cyclopropoxybenzonitrile (CAS 1243467-88-0)
- (3-Cyclopropoxy-5-iodophenyl)(methyl)sulfane (CAS 1243382-86-6)
- Methyl 2-(3-methylthiophen-2-yl)-2-oxoacetate (CAS 155299-35-7)
- NefopaM N-Oxide (CAS 66091-32-5)
- (4-Iodo-3,5-dimethylphenyl)methanol (CAS 18982-60-0)
- N-(4-ethoxyphenyl)-1-phenylcyclopentane-1-carboxamide (CAS 332392-08-2)
- 5-Methyl-4-((3-methyl-5-oxo-1-phenyl-1H-pyrazol-4(5H)-ylidene)methyl)-2-phenyl-1H-pyrazol-3(2H)-one (CAS 15900-11-5)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com