tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate CAS 347186-48-5

Purity 97%+In StockPharmaceutical Standards
CAS No.347186-48-5
Molecular FormulaC18H26N2O4
Molecular Weight334.41 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate CAS 347186-48-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 334.41 g/mol gives tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate (CAS 347186-48-5), a certified reference material (molecular formula C18H26N2O4, MW 334.41 g/mol) for analytical method development and quality control.

The molecular framework of tert-butyl 4-(2-methoxy-2-oxo-1-phenylethyl)piperazine-1-carboxylate (C18H26N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H26N2O4
Molecular Weight334.41 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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