5-(2-Chloro-6-fluorophenyl)-3-methylisoxazole-4-carbonyl chloride CAS 347186-83-8
| CAS No. | 347186-83-8 |
| Molecular Formula | C11H6Cl2FNO2 |
| Molecular Weight | 274.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-(2-Chloro-6-fluorophenyl)-3-methylisoxazole-4-carbonyl chloride (CAS 347186-83-8), a certified reference material (molecular formula C11H6Cl2FNO2, MW 274.08 g/mol) for analytical method development and quality control.
Structurally, 5-(2-Chloro-6-fluorophenyl)-3-methylisoxazole-4-carbonyl chloride (C11H6Cl2FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 274.08 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H6Cl2FNO2 |
| Molecular Weight | 274.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 3-Nitro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile (CAS 775351-58-1)
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- Cloxacillin Impurity N2 (CAS 69399-79-7)
- 6-bromo-8-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 2155875-89-9)
- 3-Methyl-1-(2-methylbenzoyl)-1H-pyrazol-5(4H)-one (CAS 101771-59-9)
- [3,5-dichloro-4-(trifluoromethyl)phenyl]methanol (CAS 1788733-89-0)
- 7-Oxa-2-azaspiro[4.5]Decan-10-one (CAS 1369346-84-8)
- N-Carbamoyl-N-phenylformamide (CAS 60561-40-2)
- Procaterol Impurity 8 (CAS CATO-C4X-18108)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-2,5-dimethyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-16-9)
- Clofarabine Impurity 11 (CAS CATO-C4X-159311)
- 4-{[3-(chloromethyl)phenyl]methyl}morpholine (CAS 778541-82-5)
- (4-Bromophenyl)(thiophen-3-yl)methanol (CAS 944696-30-4)
- Semaglutide Impurity 6 (CAS 62-57-7)
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