4-Chloro-2-(p-tolyl)quinoline-1(2H)-carbaldehyde CAS 347335-63-1
| CAS No. | 347335-63-1 |
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-2-(p-tolyl)quinoline-1(2H)-carbaldehyde is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Chloro-2-(p-tolyl)quinoline-1(2H)-carbaldehyde (CAS 347335-63-1), molecular formula C17H14ClNO and molecular weight 283.75 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-2-(p-tolyl)quinoline-1(2H)-carbaldehyde (C17H14ClNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 4-Amino-5-chloro-2-methoxy-N-(piperidin-4-yl)benzamide (CAS 57645-49-5)
- 4-Chloro-5-(cyclopropylamino)-2-(3,3-dimethyl-2-oxobutyl)pyridazin-3(2H)-one (CAS 477860-40-5)
- (5E)-2-Mercapto-5-[(2-methyl-1H-indol-3-yl)-methylene]-3-phenyl-3,5-dihydro-4H-imidazol-4-one 681014-88-0 (CAS 681014-88-0)
- N-(4-(4-pentylcyclohexyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide (CAS 866131-88-6)
- 5-amino-6-bromo-pyridine-2-carbonitrile (CAS 849353-22-6)
- Ethyl 2-chloro-6-fluoro-3-methylbenzoate (CAS 773135-50-5)
- 5-Nitropyridin-2-yl diphenylphosphinate (CAS 80944-63-4)
- (5-Bromo-1H-indazol-7-yl)methanol (CAS 1360957-64-7)
- 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)propanoic acid (CAS 680579-19-5)
- Nabumetone EP Impurity E (CAS 343272-53-7)
- 5-(pyridin-2-ylthio)furan-2-carbaldehyde (CAS 709635-68-7)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
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