Methyl 4-(chloromethyl)thiophene-2-carboxylate CAS 34767-85-6
| CAS No. | 34767-85-6 |
| Molecular Formula | C7H7ClO2S |
| Molecular Weight | 190.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 4-(chloromethyl)thiophene-2-carboxylate (CAS 34767-85-6), molecular formula C7H7ClO2S and molecular weight 190.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 4-(chloromethyl)thiophene-2-carboxylate (C7H7ClO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Methyl 4-(chloromethyl)thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClO2S |
| Molecular Weight | 190.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
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Recommended Standards
- Methyl 3-chloro-5-methylthiophene-2-carboxylate (CAS 229343-19-5)
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- Methyl 4-chlorobenzenesulfinate (CAS 26760-21-4)
- Methyl 2-(5-chlorothiophen-2-yl)acetate (CAS 71637-28-0)
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- (2S,4S)-2-Hydroxymethyl-4-Cbz-aminopyrrolidine hydrochloride (CAS 1279026-90-2)
- (2S)-5-Carbamoylpyrrolidine-2-carboxylic acid (CAS 98484-65-2)
- 3-(2-Phenyl-1H-indol-3-yl)propanoic acid (CAS 62663-27-8)
- 4-[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-pyrimidin-2-ylamine (CAS 1311279-70-5)
- 5,6,6-TRifluoro-5-hexene-2-one (CAS 155630-33-4)
- 6-Chloro-N-isopropylpyridine-2-carboxamide (CAS 157328-17-1)
- Ethyl (2Z)-2-({2-[(Z)-benzoyl]-3-oxo-3-phenylprop-1-en-1-yl}amino)-3-(dimethylamino)prop-2-enoate (CAS 219838-91-2)
- (4-Isopropyl-benzyl)-(tetrahydro-furan-2-yl-methyl)-amine (CAS 436096-82-1)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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