6-Fluoro-2-methyl-2H-indazole CAS 348-39-0
| CAS No. | 348-39-0 |
| Molecular Formula | C8H7FN2 |
| Molecular Weight | 150.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Fluoro-2-methyl-2H-indazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Fluoro-2-methyl-2H-indazole (CAS 348-39-0), molecular formula C8H7FN2 and molecular weight 150.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 6-Fluoro-2-methyl-2H-indazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 150.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7FN2 |
| Molecular Weight | 150.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 2-(5-Fluoro-6-methylpyridin-2-yl)acetonitrile (CAS 1000555-87-2)
- 2-(6-Fluoro-5-methylpyridin-3-yl)acetonitrile (CAS 1000556-88-6)
- 4-Fluoro-1H-indol-5-amine (CAS 1003858-66-9)
- 7-Fluoro-3-methyl-1h-indazole (CAS 1017682-73-3)
- 5-Fluoro-4-methyl-1H-indazole (CAS 105391-69-3)
- 6-Fluoro-4-methyl-1H-indazole (CAS 105391-75-1)
- 5-Fluoro-3-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1068976-55-5)
- 6-Fluoro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1082040-93-4)
Recommended Standards
- 6-Amino-4-fluoro-1H-indole (CAS 885518-26-3)
- 6-Fluoro-3H-indol-2-amine (CAS 769912-67-6)
- 5-Fluoro-6-methylbenzofuran (CAS 199391-67-8)
- 6-Fluoro-3-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 2231675-09-3)
- Diethyl N-[(1S)-2-methyl-1-(1-piperidinylmethyl)propyl]phosphoramidate (CAS 2417471-79-3)
- 2-[(5-chlorothiophen-2-yl)methanesulfonyl]acetic acid (CAS 851175-94-5)
- (3,4-Dichlorophenyl)(3-fluorophenyl)methanol (CAS 844683-63-2)
- (3R)-4,4-dimethylpyrrolidine-3-carboxylic acid (CAS 1314999-39-7)
- 2-[Chloro(difluoro)methoxy]-4-fluoro-1-nitro-benzene (CAS 1404193-55-0)
- 2-phenylethane-1-sulfonamide (CAS 16993-47-8)
- 3-p-Tolylsulfamoyl-benzoic acid (CAS 147410-77-3)
- (2S)-N-methyloxolane-2-carboxamide (CAS 1222386-56-2)
- 3-(1-Naphthyl)phenylboronic Acid (CAS 881913-20-8)
- Neuropeptide K, porcine (CAS 106441-70-7)
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