5-Chloro-1-(4-(methylsulfonyl)benzyl)-1H-indole CAS 348111-48-8
| CAS No. | 348111-48-8 |
| Molecular Formula | C16H14ClNO2S |
| Molecular Weight | 319.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-1-(4-(methylsulfonyl)benzyl)-1H-indole.
5-Chloro-1-(4-(methylsulfonyl)benzyl)-1H-indole (CAS 348111-48-8), molecular formula C16H14ClNO2S and molecular weight 319.81 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H14ClNO2S, 5-Chloro-1-(4-(methylsulfonyl)benzyl)-1H-indole contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 319.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14ClNO2S |
| Molecular Weight | 319.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- (R)-3-Amino-1-benzylpiperidine (CAS 168466-84-0)
- (2R,3R,4R,5R)-2-(Aminomethyl)-5-methoxytetrahydrofuran-3,4-diol (CAS 733675-00-8)
- Tizoxanide Sulfate (CAS 1391053-06-7)
- 2,2,2-Trifluoro-N-(2-methyl-4-nitrophenyl)acetamide (CAS 355809-03-9)
- Pregabalin Impurity 112 (CAS CATO-C4X-1312112)
- 6-Chloro-2-(2,5-dimethylphenyl)quinoline-4-carbonyl chloride (CAS 1160263-15-9)
- N-(((4,6-Dimethylpyrimidin-2-yl)thio)methyl)thiophene-2-carboxamide (CAS 637321-96-1)
- 5-(Thiophen-2-yl)picolinic acid (CAS 99568-12-4)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
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