(4-Fluorophenyl)phosphonic acid CAS 349-87-1
| CAS No. | 349-87-1 |
| Molecular Formula | C6H6FO3P |
| Molecular Weight | 176.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (4-Fluorophenyl)phosphonic acid is closely related to a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(4-Fluorophenyl)phosphonic acid (CAS 349-87-1), molecular formula C6H6FO3P and molecular weight 176.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4-Fluorophenyl)phosphonic acid (C6H6FO3P) is characterized by a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (4-Fluorophenyl)phosphonic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6FO3P |
| Molecular Weight | 176.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- 2-(4-Fluorophenyl)-4-methyl-1H-imidazole (CAS 104575-40-8)
- 1-(4-Fluorophenyl)-4-methyl-1H-pyrazole (CAS 1152719-74-8)
- 2-(2-Fluorophenyl)-5-methyl-1H-imidazole (CAS 1226148-59-9)
- 1-(3-Fluorophenyl)-5-methyl-1H-pyrazole (CAS 1250150-43-6)
- 1-(2-Fluorophenyl)-5-methyl-1H-pyrazole (CAS 1250516-18-7)
- 5-(2-Fluorophenyl)-2-methyl-1H-imidazole (CAS 1283851-22-8)
- 1-[(2-fluorophenyl)methyl]-1h-pyrazole (CAS 1341500-04-6)
- 1-(4-Fluorophenyl)-3-methyl-1h-pyrazole (CAS 166588-10-9)
Recommended Standards
- 4,4,5,5,5-Pentafluoropent-2-en-1-ol (CAS 148757-93-1)
- Pentafluoroethyl ethyl ketone (CAS 378-72-3)
- Benzyl-2,3,4,5,6-d5 Bromide (CAS 71258-22-5)
- 2,4,6-Trifluoro-3-hydroxybenzaldehyde (CAS 1093253-75-8)
- Ethyl 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,2-dimethylpropanoate (CAS 1934802-10-4)
- 2-(6-Ethoxy-2,3,4-trifluorophenyl)acetic acid (CAS 1980062-56-3)
- rel-(3aR,7aS)-8,8-Dimethylhexahydro-1H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide (CAS 1246038-54-9)
- Bariumhexafluoroacetylacetonate (CAS 118131-57-0)
- 2-(Ethylthio)-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carboxylic acid (CAS 1342874-92-3)
- 3-Nitro-4-(1H-pyrazol-1-yl)-N-(o-tolyl)benzamide (CAS 400080-60-6)
- 1-azido-4-bromo-2-chlorobenzene (CAS 1152943-47-9)
- N-(Thiophen-2-ylmethyl)-1-(6-(o-tolyl)pyridazin-3-yl)piperidine-4-carboxamide (CAS 1105232-97-0)
- 2,2-difluoro-1-(1-isobutyl-1h-pyraZol-4-yl)ethanone (CAS 1245823-42-0)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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