Methyl (3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carbonyl)glycinate CAS 349398-65-8

Purity 97%+In StockPharmaceutical Standards
CAS No.349398-65-8
Molecular FormulaC14H12Cl2N2O4
Molecular Weight343.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl (3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carbonyl)glycinate CAS 349398-65-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 343.16 g/mol gives Methyl (3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carbonyl)glycinate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Methyl (3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carbonyl)glycinate (CAS 349398-65-8), molecular formula C14H12Cl2N2O4 and molecular weight 343.16 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Methyl (3-(2,6-dichlorophenyl)-5-methylisoxazole-4-carbonyl)glycinate (C14H12Cl2N2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H12Cl2N2O4
Molecular Weight343.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2

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