1-Phenyl-4-(1,4-dioxaspiro[4.5]decan-8-yl)piperazine CAS 349449-96-3
| CAS No. | 349449-96-3 |
| Molecular Formula | C18H26N2O2 |
| Molecular Weight | 302.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Phenyl-4-(1,4-dioxaspiro[4.5]decan-8-yl)piperazine (C18H26N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-Phenyl-4-(1,4-dioxaspiro[4.5]decan-8-yl)piperazine (CAS 349449-96-3), molecular formula C18H26N2O2 and molecular weight 302.41 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Phenyl-4-(1,4-dioxaspiro[4.5]decan-8-yl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H26N2O2 |
| Molecular Weight | 302.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Phenyl Standards
- 1-((1,4-Dioxaspiro[4.5]decan-2-yl)methyl)-3-(m-tolyl)urea (CAS 900006-57-7)
- N-((1,4-Dioxaspiro[4.4]nonan-2-yl)methyl)-2-(4-methoxyphenyl)acetamide (CAS 899958-30-6)
- N-((1,4-Dioxaspiro[4.4]nonan-2-yl)methyl)-4-ethoxybenzamide (CAS 923232-51-3)
- N1-((1,4-Dioxaspiro[4.5]decan-2-yl)methyl)-N2-(tert-butyl)oxalamide (CAS 941914-63-2)
- N-((1,4-Dioxaspiro[4.5]decan-2-yl)methyl)-3-(thiophen-2-yl)acrylamide (CAS 1331520-30-9)
- N1-((1,4-Dioxaspiro[4.4]nonan-2-yl)methyl)-N2-cyclohexyloxalamide (CAS 899963-07-6)
- N-((1,4-Dioxaspiro[4.5]decan-2-yl)methyl)-2,5-dimethylfuran-3-carboxamide (CAS 1210896-07-3)
- 1,4-Dioxaspiro[4.5]decan-8-yl 4-methylbenzenesulfonate (CAS 23511-05-9)
Recommended Standards
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- 1,2-Bis(4-(methylthio)phenyl)ethane-1,2-dione (CAS 53458-17-6)
- 2-(2-(Phenylimino)-4-(thiophen-2-yl)thiazol-3(2H)-yl)ethan-1-ol (CAS 915186-47-9)
- 2-(Difluoromethyl)-3,4-dimethoxypyridine-5-carbonyl chloride (CAS 1806800-95-2)
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- 2-(2-Methoxyphenyl)-1,3-thiazole-5-carboxylic acid (CAS 920441-07-2)
- 1-cyclopentyl-2,2,2-trifluoroethan-1-one (CAS 101066-63-1)
- 3-(4-(Tetrahydrofuran-2-carbonyl)piperazin-1-yl)propanoic acid, potassium salt (CAS 1281154-60-6)
- 4-Methyl-8,8a-dihydropyrrolo[1,2-d][1,2,4]triazine-1,6(2H,7H)-dione (CAS 182482-39-9)
- Palmitoyl Tripeptide-1 HCl (CAS 2757690-14-3)
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