Enalapril EP Impurity C-d5 CAS 349554-00-3
| CAS No. | 349554-00-3 |
| Molecular Formula | - |
| Molecular Weight | 353.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Enalapril EP Impurity C-d5.
Enalapril EP Impurity C-d5 (CAS 349554-00-3) is a certified pharmaceutical impurity reference standard with the molecular formula C18H19D5N2O5 and a molecular weight of 353.42 g/mol.
Enalapril EP Impurity C-d5 (C18H19D5N2O5) contains deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19D5N2O5 |
| Molecular Weight | 353.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Enalapril Standards
- R-Enalapril Diketopiperazine (CAS CATO-C4X-133427)
- Enalapril EP Impurity D (CAS 115729-52-7)
- Enalapril (CAS 75847-73-3)
- Enalapril EP Impurity A (CAS 76420-74-1)
- Enalapril Diketopiperazine Acid (R-Isomer) (CAS 219677-80-2)
- Enalapril Maleate Impurity 26 (CAS 115623-21-7)
- Enalapril Impurity 35 (CAS CATO-C4X-133435)
- Enalapril Impurity 39 (CAS 2055735-10-7)
Recommended Standards
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- Epinastine Impurity 30 (CAS CATO-C4X-184030)
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- Boc-(4S,2RS)-2-phenylthiazolidine-4-carboxylic acid (CAS 637032-03-2)
- 3-{[2-(1-Cyclohexen-1-yl)ethyl]amino}-N-ethylpropanamide (CAS 1040691-15-3)
- 3,5,7-trichloropyrazolo[1,5-a]pyrimidine (CAS 58347-52-7)
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- N-(2,4-Dimethylphenyl)-2-((4-(4-methoxyphenyl)-5-(phenoxymethyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 539808-59-8)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
Why CATO?
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