N,N-dimethyl-4-(4-nitrophenyl)piperazine-1-sulfonamide CAS 349573-54-2
| CAS No. | 349573-54-2 |
| Molecular Formula | C12H18N4O4S |
| Molecular Weight | 314.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N,N-dimethyl-4-(4-nitrophenyl)piperazine-1-sulfonamide (CAS 349573-54-2) is a high-purity analytical reference standard with the molecular formula C12H18N4O4S and a molecular weight of 314.36 g/mol.
The molecular framework of N,N-dimethyl-4-(4-nitrophenyl)piperazine-1-sulfonamide (C12H18N4O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N,N-dimethyl-4-(4-nitrophenyl)piperazine-1-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18N4O4S |
| Molecular Weight | 314.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Recommended Standards
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- Maropitant Impurity 2(M11) (CAS 85943-26-6)
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- Lixisenatide (CAS 320367-13-3（free base）)
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