N-{[(4-chlorophenyl)carbamoyl]amino}thiophene-2-carboxamide CAS 349613-62-3
| CAS No. | 349613-62-3 |
| Molecular Formula | C12H10ClN3O2S |
| Molecular Weight | 295.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-{[(4-chlorophenyl)carbamoyl]amino}thiophene-2-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-{[(4-chlorophenyl)carbamoyl]amino}thiophene-2-carboxamide (CAS 349613-62-3), a certified reference material (molecular formula C12H10ClN3O2S, MW 295.74 g/mol) for analytical method development and quality control.
Structurally, N-{[(4-chlorophenyl)carbamoyl]amino}thiophene-2-carboxamide (C12H10ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 295.74 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-{[(4-chlorophenyl)carbamoyl]amino}thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN3O2S |
| Molecular Weight | 295.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
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- 1-[(2-Chlorophenyl)methanesulfinyl]-2-nitrobenzene (CAS 955965-74-9)
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Recommended Standards
- methyl 3-[(2-chlorobenzoyl)amino]-2-thiophenecarboxylate (CAS 478080-02-3)
- Thiamethoxam D4 (oxadiazine D4) (CAS 1331642-98-8)
- Methyl 3-(4-chlorobenzamido)thiophene-2-carboxylate (CAS 544421-24-1)
- Tizanidine impurity 21 (CAS CATO-C4X-144521)
- tert-butyl (1-benzoyl-4-methylpiperidin-4-yl)carbamate (CAS 1262787-56-3)
- 1-((4-Chloro-1,3-dimethyl-1h-pyrazol-5-yl)methyl)-1h-1,2,3-triazol-4-amine (CAS 1525902-72-0)
- N-(3-chlorophenyl)-2-(m-tolylthio)acetamide (CAS 329079-28-9)
- 1-Benzyl-N-(4-chlorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxamide (CAS 338748-85-9)
- 1,3,5-Triacetylbenzene (CAS 779-90-8)
- Angiotensin I Converting Enzyme Inhibitor (CAS 30892-86-5)
- ((4-Bromopentyl)oxy)benzene (CAS 861374-33-6)
- 2-fluoro-4-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1177009-38-9)
- 2-Amino-2,4-dimethylpentanenitrile hydrochloride (CAS 52161-39-4)
- Semaglutide impurity 259 (CAS CATO-C4X-2226259)
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