Methyl 2-amino-4-(4-fluorophenyl)-5-methylthiophene-3-carboxylate CAS 350992-29-9

Purity 97%+In StockPharmaceutical Standards
CAS No.350992-29-9
Molecular FormulaC13H12FNO2S
Molecular Weight265.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 2-amino-4-(4-fluorophenyl)-5-methylthiophene-3-carboxylate CAS 350992-29-9 chemical structure

Description

The occurrence of Methyl 2-amino-4-(4-fluorophenyl)-5-methylthiophene-3-carboxylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Methyl 2-amino-4-(4-fluorophenyl)-5-methylthiophene-3-carboxylate (CAS 350992-29-9), a certified reference material (molecular formula C13H12FNO2S, MW 265.30 g/mol) for analytical method development and quality control.

The molecular framework of Methyl 2-amino-4-(4-fluorophenyl)-5-methylthiophene-3-carboxylate (C13H12FNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H12FNO2S
Molecular Weight265.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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