Pirfenidone Impurity 42 CAS 3510-66-5
| CAS No. | 3510-66-5 |
| Molecular Formula | C6H6BrN |
| Molecular Weight | 172.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pirfenidone Impurity 42.
As a process- or degradation-related impurity, Pirfenidone Impurity 42 (CAS 3510-66-5, C6H6BrN) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, bromine substitution, an aromatic ring system, Pirfenidone Impurity 42 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 172.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6BrN |
| Molecular Weight | 172.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Pirfenidone Standards
- Pirfenidone Impurity 35 (CAS 2412-49-9)
- Pirfenidone Impurity 32 (CAS 92-53-5)
- Pirfenidone (CAS 53179-13-8)
- Pirfenidone Impurity 14 (CAS 51933-81-4)
- Pirfenidone Impurity 29 (CAS 53427-93-3)
- Pirfenidone Impurity 30 (CAS CATO-C4X-222930)
- Pirfenidone Impurity 31 (CAS 13179-27-6)
- Pirfenidone Impurity 6 (CAS 2640792-41-0)
Recommended Standards
- Phloroglucinol Impurity 22 (CAS 106-40-1)
- 2-Ethoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1126-93-8)
- Erlotinib Impurity 40 (CAS 591-19-5)
- (1-isobutyl-1H-pyrazol-4-yl)boronic acid (CAS 929094-25-7)
- Amoxicillin EP Impurity O（Mixture）(Discontinued,See C4X-114824) (CAS CATO-C4X-114826)
- Olopatadine Impurity 29 (CAS 156-38-7)
- Deoxycholic acid Impurity 14 (CAS 1334203-40-5)
- Phenoxypropazine (CAS 3818-37-9)
- (4-Chlorophenyl)[2-(2,4-dichlorophenyl)cyclopropyl]methanone (CAS 338401-29-9)
- (2,4-di-tert-butylphenoxy)acetic acid 18327-79-2 2-[2,4-di(tert-butyl)phenoxy]acetic acid (CAS 18327-79-2)
- 1,1,1-Trifluoro-3-(5-methylpyridin-2-yl)propan-2-ol (CAS 1502999-26-9)
- (2,2-Dimethyl-1,2-dihydrobenzo[f]isoquinolin-4-yl)glycine (CAS 307924-32-9)
- ((1S,3R)-1-Isopropyl-3-(((3S,4R)-3-methoxytetrahydro-2H-pyran-4-yl)amino)cyclopentyl)(3-(trifluoromethyl)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)methanone succinate (CAS 624733-89-7)
- Gastrin Tetrapeptide (CAS 1947-37-1)
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