2,5-Bis(trifluoromethyl)benzenesulfonyl Chloride CAS 351003-22-0
| CAS No. | 351003-22-0 |
| Molecular Formula | C8H3ClF6O2S |
| Molecular Weight | 312.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,5-Bis(trifluoromethyl)benzenesulfonyl Chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,5-Bis(trifluoromethyl)benzenesulfonyl Chloride (CAS 351003-22-0), molecular formula C8H3ClF6O2S and molecular weight 312.62 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,5-Bis(trifluoromethyl)benzenesulfonyl Chloride (C8H3ClF6O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 312.62 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,5-Bis(trifluoromethyl)benzenesulfonyl Chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3ClF6O2S |
| Molecular Weight | 312.62 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Bis Standards
- 2,4-Bis(trifluoromethyl)benzenesulfonyl chloride (CAS 376637-88-6)
- 3,5-Bis(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 39234-86-1)
- 1-(4-(Trifluoromethyl)pyrimidin-2-yl)-1H-pyrazole-4-sulfonyl chloride (CAS 1215564-15-0)
- ((4-(Trifluoromethyl)cyclopent-1-ene-1,2-diyl)bis(oxy))bis(trimethylsilane) (CAS 1707568-75-9)
- 2-(4-(Trifluoromethyl)phenyl)-7,8-dihydro-3H-thiopyrano[3,2-d]pyrimidin-4(6H)-one (CAS 1450790-46-1)
- Ethyl 5-(trifluoromethyl)-1-(4-fluorophenyl)-1<I>H</I>-pyrazole-4-carboxylate (CAS 175137-38-9)
- Ethyl ((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)glycinate (CAS 1355334-83-6)
- 5-(3-(2-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)thiazol-2-amine (CAS 1707371-62-7)
Recommended Standards
- [1,2,5]Selenadiazolo[3,4-d]pyrimidine-5,7(3H,6H)-dione (CAS 7698-95-5)
- N-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]methoxy}-N-[(hydroxyimino)methyl]urea (CAS 400087-73-2)
- tert-Butyl (5-bromo-2-chlorothiophen-3-yl)carbamate (CAS 2567558-28-3)
- CAS 33512-37-7 (CAS 33512-37-7)
- 5-Bromo-1-(cyclopropylmethyl)-1H-1,2,4-triazole (CAS 2091652-88-7)
- Methyl 5-bromo-4-methoxynicotinate (CAS 1256813-81-6)
- N,N-Diallyl-2-aminoacetamide hydrochloride (CAS 118870-91-0)
- L-2-Nitrophenylalanine (CAS 19883-75-1)
- (2E)-N-[(4-Fluorophenyl)methyl]-3-(3-methylphenyl)prop-2-enamide (CAS 329779-81-9)
- trans-4-(4-Methylpiperazin-1-yl)pyrrolidin-3-ol trihydrochloride (CAS 1262769-85-6)
- 2-(m-Tolyl)quinazoline (CAS 1208259-19-1)
- 1-(bromomethyl)-3-(trideuteriomethyl)benzene (CAS 114563-28-9)
- Kaurenol (CAS 2300-11-0)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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