4-(Difluoromethoxy)benzenesulfonyl Chloride CAS 351003-34-4
| CAS No. | 351003-34-4 |
| Molecular Formula | C7H5ClF2O3S |
| Molecular Weight | 242.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(Difluoromethoxy)benzenesulfonyl Chloride (CAS 351003-34-4), molecular formula C7H5ClF2O3S and molecular weight 242.63 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H5ClF2O3S, 4-(Difluoromethoxy)benzenesulfonyl Chloride contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 242.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2O3S |
| Molecular Weight | 242.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
- 2-(Difluoromethoxy)benzenesulfonyl chloride (CAS 77798-10-8)
- 1-[4-(difluoromethoxy)phenyl]piperidin-4-amine (CAS 1094308-87-8)
- 1-(4-(Difluoromethoxy)benzyl)piperazine (CAS 1150344-90-3)
- 1-[4-(difluoromethoxy)phenyl]piperidin-3-amine (CAS 1282711-39-0)
- 4-[4-(difluoromethoxy)phenyl]-1,3-thiazol-2-amine (CAS 105512-78-5)
- 4-(3-(Difluoromethoxy)phenyl)thiazol-2(3h)-imine (CAS 1094363-93-5)
- 4-[2-(difluoromethoxy)phenyl]-1,3-thiazol-2-amine (CAS 760936-33-2)
- 3-(Difluoromethoxy)-5-methylbenzofuran-2-carboxylic acid (CAS 1708401-49-3)
Recommended Standards
- 5-(chloromethyl)-3-[(4-fluorophenoxy)methyl]-1,2,4-oxadiazole (CAS 929975-09-7)
- 1-(2-chloro-3-fluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 2028797-37-5)
- 4-Cyanobenzo[d]oxazole-2-sulfonyl chloride (CAS 1806571-84-5)
- 4-Amino-5-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1806777-00-3)
- (S)-2-((Diphenylphosphoryl)amino)-3-phenylpropanoic acid (CAS 62056-93-3)
- benzyl(1H-pyrazol-3-ylmethyl)amine hydrochloride (CAS 1258650-90-6)
- 3-(4-Allyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)-1-(2,4-dichlorobenzyl)pyridin-2(1H)-one (CAS 477853-06-8)
- 1,11-diazide-3,6,9-triox undecane (CAS 101187-39-7)
- 2-(4-pyridyl)propanedial (CAS 51076-46-1)
- 1-Propylnaphthalene (CAS 2765-18-6)
- 1-(5-tert-Butyl-1,2-oxazol-3-yl)-3-methylurea (CAS 55807-46-0)
- 3-Methyl-3-azabicyclo[3.2.1]octan-8-one (CAS 4146-34-3)
- 3-(4,4,4-Trifluoro-3-oxobutanoyl)benzonitrile (CAS 846601-25-0)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com