3-Chloro-2-fluorobenzenesulfonyl Chloride CAS 351003-48-0
| CAS No. | 351003-48-0 |
| Molecular Formula | C6H3Cl2FO2S |
| Molecular Weight | 229.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 3-Chloro-2-fluorobenzenesulfonyl Chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 229.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 3-Chloro-2-fluorobenzenesulfonyl Chloride (CAS 351003-48-0), a certified reference material (molecular formula C6H3Cl2FO2S, MW 229.06 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-2-fluorobenzenesulfonyl Chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl2FO2S |
| Molecular Weight | 229.06 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-5-fluorobenzenesulfonyl chloride (CAS 1131397-73-3)
- 2-Chloro-6-fluorobenzene-1-sulfonyl chloride (CAS 1208075-25-5)
- 4-Chloro-2-fluorobenzenesulfonyl chloride (CAS 141337-26-0)
- 7-Chloro-2-(chloromethyl)pyrido[1,2-a]pyrimidin-4-one (CAS 162469-87-6)
- 2-Chloro-n-(5-chloro-2-cyanophenyl)acetamide (CAS 189083-68-9)
- 2-Chloro-3-fluorobenzenesulfonyl chloride (CAS 504424-79-7)
- 2-Chloro-4-fluorobenzenesulfonyl Chloride (CAS 85958-57-2)
- 2-Chloro-5-fluorobenzenesulfonyl Chloride (CAS 82875-86-3)
Recommended Standards
- 3-Chloro-2-(chloromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 87779-03-1)
- 3-Chloro-4-fluorobenzene-1-sulfonyl chloride (CAS 91170-93-3)
- 3-Amino-5,7-dichloroquinolin-8-ol (CAS 648896-75-7)
- 3-Chloro-7-(chloromethyl)-1,5-naphthyridin-2(1H)-one (CAS 2855981-77-8)
- 3-(2,2,2-Trifluoroethoxy)pyrrolidine (CAS 1247463-30-4)
- 3-[3-(4-Morpholinyl)propoxy]benzaldehyde (CAS 82625-44-3)
- B I09 (CAS 1607803-67-7)
- Methyl 3-(pyrrolidin-3-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxylate dihydrochloride (CAS 1416440-67-9)
- 3,7,8-Trimethyl-1,5-dihydrobenzo[e][1,3]dithiepine (CAS 10153-31-8)
- N-(4-(N-Mesitylsulfamoyl)phenyl)acetamide (CAS 294885-60-2)
- Vonoprazan Fumarate Impurity 27 (CAS CATO-C4X-102027)
- Morin Hydrate (CAS 654055-01-3)
- 1-(4-(((3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl)amino)phenyl)butan-1-one (CAS 1091670-52-8)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
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