Ethyl 2-amino-4-(4-ethoxyphenyl)-5-methylthiophene-3-carboxylate CAS 351158-30-0

Description

Compared with other compounds in its class, the molecular weight of 305.39 g/mol gives Ethyl 2-amino-4-(4-ethoxyphenyl)-5-methylthiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Ethyl 2-amino-4-(4-ethoxyphenyl)-5-methylthiophene-3-carboxylate (CAS 351158-30-0), a certified reference material (molecular formula C16H19NO3S, MW 305.39 g/mol) for analytical method development and quality control.

The molecular framework of Ethyl 2-amino-4-(4-ethoxyphenyl)-5-methylthiophene-3-carboxylate (C16H19NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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