7-Methyl-2H-pyrazolo[3,4-b]quinolin-3-amine CAS 351357-44-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Methyl-2H-pyrazolo[3,4-b]quinolin-3-amine.

7-Methyl-2H-pyrazolo[3,4-b]quinolin-3-amine (CAS 351357-44-3), molecular formula C11H10N4 and molecular weight 198.22 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 7-Methyl-2H-pyrazolo[3,4-b]quinolin-3-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 198.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Methyl-2H-pyrazolo[3,4-b]quinolin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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