n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide CAS 351424-40-3

Purity 97%+In StockPharmaceutical Standards
CAS No.351424-40-3
Molecular FormulaC12H12N2OS
Molecular Weight232.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide CAS 351424-40-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 232.30 g/mol gives n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide (CAS 351424-40-3) is a high-purity analytical reference standard with the molecular formula C12H12N2OS and a molecular weight of 232.30 g/mol.

The molecular framework of n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide (C12H12N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), n-(4-Amino-2-methylphenyl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H12N2OS
Molecular Weight232.30 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2
Sulfur Atoms1

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