Tetraphenylphosphonium thiocyanate CAS 35171-64-3
| CAS No. | 35171-64-3 |
| Molecular Formula | C24H20P |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tetraphenylphosphonium thiocyanate.
Tetraphenylphosphonium thiocyanate (CAS 35171-64-3) is a high-purity analytical reference standard with the molecular formula C24H20PCNS and a molecular weight of 397.48 g/mol.
The molecular framework of Tetraphenylphosphonium thiocyanate (C24H20PCNS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, organophosphorus functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H20P CNS |
| Molecular Weight | 397.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Tetraphenylphosphonium Standards
- Tetraphenylphosphonium chloride hydrate (CAS 123557-24-4)
- Tetraphenylphosphonium hexafluoroantimonate (CAS 124329-50-6)
- Tetraphenylphosphonium phenolate (CAS 15464-47-8)
- Tetraphenylphosphonium Tetraphenylborate (CAS 15525-15-2)
- Tetraphenylphosphonium Tetra-p-tolylborate (CAS 181259-35-8)
- 2001-45-8 Tetraphenylphosphonium chloride phosphonium, tetraphenyl-, chloride tetraphenylchlorophosphine tetraphenylphosphanium chloride tetraphenylphosphonium chlorid tetraphenylphosphonium chloride, c 73.8%, h 5.5% tetraphenylphosphonium chloride,98% tetraphenylphosponium chloride (CAS 2001-45-8)
- Tetraphenylphosphonium Iodide (CAS 2065-67-0)
- 2751-90-8 Tetraphenylphosphonium bromide Phosphonium, tetraphenyl-, bromide (1:1) Phosphonium, tetraphenyl-, bromide EINECS 220-393-4 (CAS 2751-90-8)
Recommended Standards
- 3-{4-chloropyrrolo[2,1-f][1,2,4]triazin-7-yl}propan-1-amine (CAS 1547022-76-3)
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- D-β-Asp15-Tirzepatide (CAS CATO-CPTD788930)
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