351893-52-2 5-Chloro-4-hydroxy-8-methylquinoline-3-carboxylic acid ethyl ester ethyl 5-chloro-4-hydroxy-8-methylquinoline-3-carboxylate CAS 351893-52-2
| CAS No. | 351893-52-2 |
| Molecular Formula | C13H22ClNO3 |
| Molecular Weight | 275.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 351893-52-2 5-Chloro-4-hydroxy-8-methylquinoline-3-carboxylic acid ethyl ester ethyl 5-chloro-4-hydroxy-8-methylquinoline-3-carboxylate (CAS 351893-52-2), a certified reference material (molecular formula C13H22ClNO3, MW 275.77 g/mol) for analytical method development and quality control.
The molecular framework of 351893-52-2 5-Chloro-4-hydroxy-8-methylquinoline-3-carboxylic acid ethyl ester ethyl 5-chloro-4-hydroxy-8-methylquinoline-3-carboxylate (C13H22ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 351893-52-2 5-Chloro-4-hydroxy-8-methylquinoline-3-carboxylic acid ethyl ester ethyl 5-chloro-4-hydroxy-8-methylquinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H22ClNO3 |
| Molecular Weight | 275.77 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-(4-ethoxybenzyl)-4-methylaniline (CAS 1036537-11-7)
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- N-[2-(4-Chloro-3-methylphenoxy)ethyl]-4-methylaniline (CAS 1040688-75-2)
- 1-(2-Chloro-3-ethylquinolin-6-yl)-3-methylbutan-1-one (CAS 409340-62-1)
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Recommended Standards
- 22931-71-1 4-Chloro-6-methoxy-quinoline-3-carboxylic acid ethyl ester Ethyl 4-chloro-6-methoxyquinoline-3-carboxylate (CAS 22931-71-1)
- 1-(Benzhydrylamino)-3-chloropropan-2-ol (CAS 63477-43-0)
- N-[2-(4-Chlorophenoxy)ethyl]-2,4-dimethylaniline (CAS 356537-16-1)
- 1-(4-Chlorophenyl)-3-cyclohexyl-1H-pyrazol-5-amine (CAS 1225929-99-6)
- Methyl-1-(6-tert-butyldimethylsylyl-4’-hydroxyraloxifene)-2,3,4-tri-O-acetyl-β-D-glycopyranuronate (CAS 174264-48-3)
- 5-methyl-4-phenyl-2-(pyrrolidin-2-yl)-1H-imidazole (CAS 1153103-65-1)
- Tetrahydro-2-methyl-3-furanmethanol (CAS 39161-15-4)
- 1-(Cyclopropylamino)butan-2-ol (CAS 1183482-75-8)
- 3-(Methylthio)-2-phenylquinoline-4-carboxylic acid (CAS 400079-66-5)
- 5-ethynyl-1H-imidazole (CAS 57121-48-9)
- 2-Morpholinothiazole-5-carbaldehyde (CAS 1011-41-2)
- 3-Oxoisoindoline-4-carboxamide (CAS 935269-26-4)
- Ethyl 3-(6-fluoropyridin-3-yl)propiolate (CAS 2797070-35-8)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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