Ethyl 2-amino-4-(2,4-dichlorophenyl)thiophene-3-carboxylate CAS 351977-69-0
| CAS No. | 351977-69-0 |
| Molecular Formula | C13H11Cl2NO2S |
| Molecular Weight | 316.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2-amino-4-(2,4-dichlorophenyl)thiophene-3-carboxylate (C13H11Cl2NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Ethyl 2-amino-4-(2,4-dichlorophenyl)thiophene-3-carboxylate (CAS 351977-69-0) is a high-purity analytical reference standard with the molecular formula C13H11Cl2NO2S and a molecular weight of 316.20 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H11Cl2NO2S |
| Molecular Weight | 316.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-amino-4-(2,3-dichlorophenyl)thiophene-3-carboxylate (CAS 1101067-95-1)
- Ethyl 2-amino-4-(3,4-dichlorophenyl)thiophene-3-carboxylate (CAS 351156-69-9)
- Ethyl 3-amino-5-(2,4-dichlorophenyl)thiophene-2-carboxylate (CAS 730949-95-8)
- Methyl 2-amino-4-(2,4-dichlorophenyl)-5-methylthiophene-3-carboxylate (CAS 350989-98-9)
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Recommended Standards
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- 7-Methoxy-2,2-bis(trifluoromethyl)chroman-4-ol (CAS 609346-78-3)
- Ethyl 4,6-dichloro-2-(methylthio)quinoline-3-carboxylate (CAS 227958-96-5)
- (R)-1-(Pyridin-4-yl)ethanol (CAS 27854-88-2)
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- N,N'-bis(4-methylpyridin-2-yl)methanediamine (CAS 344303-26-0)
- 3,4-Dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid (CAS 1007875-95-7)
- 1-(Methoxymethyl)cyclohex-3-ene-1-carboxylic acid (CAS 1934407-34-7)
- (3S,4S)-3-methyl-4-(trifluoromethyl)pyrrolidine (CAS 2173996-74-0)
- 2-Chloro-N-{5H-chromeno[4,3-d]pyrimidin-2-yl}benzamide (CAS 866041-25-0)
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- 3-(Pyrrolidin-1-ylmethyl)benzoic acid (CAS 884507-41-9)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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