Ethyl (E)-3-(4-fluorophenyl)acrylate CAS 352-03-4
| CAS No. | 352-03-4 |
| Molecular Formula | C11H11FO2 |
| Molecular Weight | 194.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl (E)-3-(4-fluorophenyl)acrylate (CAS 352-03-4), molecular formula C11H11FO2 and molecular weight 194.20 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl (E)-3-(4-fluorophenyl)acrylate (C11H11FO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 194.20 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl (E)-3-(4-fluorophenyl)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11FO2 |
| Molecular Weight | 194.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Recommended Standards
- Ethyl (E)-3-(2-fluorophenyl)acrylate (CAS 89760-42-9)
- Ethyl (Z)-3-(2-fluorophenyl)acrylate (CAS 89760-43-0)
- Cyclopropyl(3-fluoro-4-methoxyphenyl)methanone (CAS 943116-00-5)
- Ethyl 2-(4-fluorophenyl)acrylate (CAS 72800-64-7)
- 4-BROMO-1-(BROMOMETHYL)-2-NITROBENZENE 4-BROMO-2-NITROBENZYL BROMIDE 5-BROMO-2-(BROMOMETHYL)NITROBENZENE 82420-34-6 BC005089 (CAS 82420-34-6)
- tert-Butyl N-ethyl-N-(3-hydroxyphenyl)carbamate (CAS 1695391-54-8)
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