Tretinoin Impurity 22 CAS 352199-94-1
| CAS No. | 352199-94-1 |
| Molecular Formula | C15H24O |
| Molecular Weight | 220.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tretinoin Impurity 22 (CAS 352199-94-1) is a certified pharmaceutical impurity reference standard with the molecular formula C15H24O and a molecular weight of 220.35 g/mol.
Structurally, Tretinoin Impurity 22 (C15H24O) contains a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 220.35 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H24O |
| Molecular Weight | 220.35 g/mol |
| Purity | >95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Tretinoin Standards
- Tretinoin Impurity 23 (CAS CATO-C4X-196923)
- Tretinoin Impurity 31 (CAS CATO-C4X-196931)
- Tretinoin Impurity 21 (CAS CATO-C4X-196921)
- Tretinoin Impurity 15 (CAS 49816-69-5)
- Tretinoin Impurity 35 (CAS CATO-C4X-196935)
- Tretinoin Impurity 2 (CAS 65812-13-7)
- Tretinoin Impurity 32 (CAS CATO-C4X-196932)
- Tretinoin Impurity 1 (CAS 41144-95-0)
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- Cytarabine Impurity 10 (CAS CATO-C4X-200510)
- Lercanidipine Impurity 37 (CAS 75130-34-6)
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