6-Bromo-3-(2-fluorophenyl)-2-methylquinazolin-4(3H)-one CAS 352346-59-9

Purity 97%+In StockPharmaceutical Standards
CAS No.352346-59-9
Molecular FormulaC15H10BrFN2O
Molecular Weight333.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-3-(2-fluorophenyl)-2-methylquinazolin-4(3H)-one CAS 352346-59-9 chemical structure

Description

The occurrence of 6-Bromo-3-(2-fluorophenyl)-2-methylquinazolin-4(3H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Bromo-3-(2-fluorophenyl)-2-methylquinazolin-4(3H)-one (CAS 352346-59-9), molecular formula C15H10BrFN2O and molecular weight 333.16 g/mol, is a CATO reference standard with documented purity and traceability.

6-Bromo-3-(2-fluorophenyl)-2-methylquinazolin-4(3H)-one (C15H10BrFN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Bromo-3-(2-fluorophenyl)-2-methylquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H10BrFN2O
Molecular Weight333.16 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Br-containing
Nitrogen Atoms2

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