(1R,2S)-2-((tert-Butoxycarbonyl)amino)cyclohexane-1-carboxylicacid CAS 352356-38-8
| CAS No. | 352356-38-8 |
| Molecular Formula | C12H21NO4 |
| Molecular Weight | 243.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(1R,2S)-2-((tert-Butoxycarbonyl)amino)cyclohexane-1-carboxylicacid (CAS 352356-38-8) is a high-purity analytical reference standard with the molecular formula C12H21NO4 and a molecular weight of 243.30 g/mol.
The molecular framework of (1R,2S)-2-((tert-Butoxycarbonyl)amino)cyclohexane-1-carboxylicacid (C12H21NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (1R,2S)-2-((tert-Butoxycarbonyl)amino)cyclohexane-1-carboxylicacid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H21NO4 |
| Molecular Weight | 243.30 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (1R,2R)-N-Ethyl-2-fluoro-N-phenylcyclopropane-1-sulfonamide (CAS 2375924-20-0)
- (1R,3R)-3-((tert-butoxycarbonyl)amino)-1-methylcyclopentane-1-carboxylic acid (CAS 2287346-23-8)
- (1R,2R)-2-tert-Butoxycarbonylamino-cyclohexanecarboxylic acid (CAS 233661-54-6)
- (1R,3S)-3-((tert-Butoxycarbonyl)amino)cyclohexanecarboxylic acid (CAS 222530-39-4)
- 4-Chloro-6-methoxy-2-(trifluoromethyl)quinazoline (CAS 338739-38-1)
- 3-Amino-1-(4-bromophenyl)pyrrolidin-2-one (CAS 1251217-15-8)
- 3-(5-Chloro-1-((tetrahydrofuran-2-yl)methyl)-1H-benzo[d]imidazol-2-yl)propanoic acid (CAS 1437485-57-8)
- 4-(2-(2-Oxobenzo[d]oxazol-3(2H)-yl)ethoxy)benzaldehyde (CAS 142649-91-0)
- (S)-2-Amino-1-((S)-2-((benzyl(methyl)amino)methyl)pyrrolidin-1-yl)propan-1-one (CAS 1401667-66-0)
- 5-Chloro-2-methoxy-6-nitro-1,8-naphthyridine (CAS 2636814-69-0)
- n-Methyl-2,3-dihydro-1h-indole-6-sulfonamide (CAS 1300027-05-7)
- tert-Butyl 3-(2-chloropyrimidin-4-yl)-1H-pyrrolo[2,3-c]pyridine-1-carboxylate (CAS 1174038-68-6)
- Tert-butyl 4-(tert-butyl)-3-(hydroxymethyl)-2-methylpiperazine-1-carboxylate (CAS 2366181-82-8)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
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