(3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid CAS 352525-85-0
| CAS No. | 352525-85-0 |
| Molecular Formula | C7H7BBrFO3 |
| Molecular Weight | 248.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid (CAS 352525-85-0), molecular formula C7H7BBrFO3 and molecular weight 248.84 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, (3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 248.84 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7BBrFO3 |
| Molecular Weight | 248.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- (3-Bromo-2-fluoro-6-methoxyphenyl)boronic acid (CAS 1309980-91-3)
- 2-Bromo-3-fluoro-6-methoxyphenylboronic acid (CAS 1315339-47-9)
- 2-Bromo-4-methoxy-6-fluorophenylboronic acid (CAS 1315476-03-9)
- (2-Bromo-6-fluoro-3-methoxyphenyl)boronic acid (CAS 957062-89-4)
- (4-Bromo-2-fluoro-6-methoxyphenyl)boronic acid (CAS 957035-32-4)
- (6-Bromo-2-fluoro-3-methoxyphenyl)boronic acid (CAS 871126-17-9)
- (6-Bromo-3-fluoro-2-methoxyphenyl)boronic acid (CAS 957035-08-4)
- 3-Bromo-6-fluoro-2-methoxyphenylboronic Acid (CAS 957120-30-8)
Recommended Standards
- 2,4,6-Trimethyl-1,3,5-tripropyl-1,3,5,2,4,6-triazatriborinane (CAS 53340-69-5)
- 4-Bromo-2-fluoro-3-methoxyphenylboronic acid (CAS 943830-77-1)
- Bupropion D9 (CAS 150988-80-0)
- 5-Bromo-2-fluoro-3-methoxyphenylboronic acid (CAS 2377610-06-3)
- 4-(4-Amino-5-methyl-1H-pyrazol-1-yl)benzoic Acid (CAS 956200-57-0)
- 4-(1-methyl-1H-pyrazol-4-yl)piperidine hydrochloride (CAS 1803586-75-5)
- 4-[1-(4-Methylphenyl)-6-(methylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]morpholine (CAS 478081-04-8)
- (R)-2-(2,4-Difluorophenyl)pyrrolidine (CAS 1228569-91-2)
- 2-(3-Chlorophenyl)-5-((3-methylpiperidin-1-yl)methyl)benzo[d]oxazole (CAS 1706443-73-3)
- 2-Ethyl-3-isopropylphenol (CAS 35050-93-2)
- (2E)-N-(3,4-Difluorophenyl)-3-[4-(2-methylpropyl)phenyl]prop-2-enamide (CAS 329778-54-3)
- Ethyl 2-(4-oxo-1-phenyl-1,4-dihydro-5h-pyrazolo[3,4-d]pyrimidin-5-yl)acetate (CAS 656831-55-9)
- (2,5-Dimethylphenyl)(2-(pyrrolidin-1-ylmethyl)phenyl)methanone (CAS 898774-61-3)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com