3-Bromo-2-fluorophenylboronic Acid CAS 352535-97-8

Purity 97%+In StockPharmaceutical Standards
CAS No.352535-97-8
Molecular FormulaC6H5BBrFO2
Molecular Weight218.82 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Bromo-2-fluorophenylboronic Acid CAS 352535-97-8 chemical structure

Description

The occurrence of 3-Bromo-2-fluorophenylboronic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Bromo-2-fluorophenylboronic Acid (CAS 352535-97-8), molecular formula C6H5BBrFO2 and molecular weight 218.82 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 3-Bromo-2-fluorophenylboronic Acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Bromo-2-fluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H5BBrFO2
Molecular Weight218.82 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2025
Halogen ContentF/Br-containing

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