2-Chloro-6-(thiophen-2-yl)pyridine CAS 35299-70-8
| CAS No. | 35299-70-8 |
| Molecular Formula | C9H6ClNS |
| Molecular Weight | 195.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-(thiophen-2-yl)pyridine (CAS 35299-70-8) is a high-purity analytical reference standard with the molecular formula C9H6ClNS and a molecular weight of 195.67 g/mol.
2-Chloro-6-(thiophen-2-yl)pyridine (C9H6ClNS) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-6-(thiophen-2-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNS |
| Molecular Weight | 195.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(5-Chloro-2-thienyl)pyridine (CAS 123784-09-8)
- 2-Chloro-4-(thiophen-2-yl)pyridine (CAS 1289555-51-6)
- 5-Chloro-4-phenylthiazole (CAS 1403935-14-7)
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Recommended Standards
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