Thiazolo[4,5-h]isoquinolin-2(3H)-one CAS 35317-84-1

Description

Compared with other compounds in its class, the molecular weight of 202.23 g/mol gives Thiazolo[4,5-h]isoquinolin-2(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Thiazolo[4,5-h]isoquinolin-2(3H)-one (CAS 35317-84-1) is a high-purity analytical reference standard with the molecular formula C10H6N2OS and a molecular weight of 202.23 g/mol.

The molecular framework of Thiazolo[4,5-h]isoquinolin-2(3H)-one (C10H6N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Thiazolo[4,5-h]isoquinolin-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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