8-Chloro-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 353258-25-0
| CAS No. | 353258-25-0 |
| Molecular Formula | C14H7ClF4N2 |
| Molecular Weight | 314.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 8-Chloro-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 353258-25-0), a certified reference material (molecular formula C14H7ClF4N2, MW 314.67 g/mol) for analytical method development and quality control.
Structurally, 8-Chloro-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (C14H7ClF4N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 314.67 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H7ClF4N2 |
| Molecular Weight | 314.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-CHLORO-2-(4-FLUOROPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE (CAS 1420885-98-8)
- 2-(2-Chloro-4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine (CAS 372122-57-1)
- 2-((7-Chloro-4-nitrobenzo[c][1,2,5]oxadiazol-5-yl)amino)ethyl propionate (CAS 705952-09-6)
- (E)-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]phenyl}methylidene)(methoxy)amine (CAS 1092343-90-2)
- 5-(Chloro(4-(trifluoromethyl)phenyl)methyl)benzo[d][1,3]dioxole (CAS 1417543-27-1)
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Recommended Standards
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- Sitafloxacin impurity 56 (CAS CATO-C4X-115556)
- 4-(Aminomethyl)-5-cyano-2-(trifluoromethoxy)benzene-1-sulfonyl chloride (CAS 1807089-48-0)
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Why CATO?
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