8-Chloro-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine-2-carboxamide CAS 353258-67-0
| CAS No. | 353258-67-0 |
| Molecular Formula | C16H8ClF6N3O |
| Molecular Weight | 407.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Chloro-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine-2-carboxamide (CAS 353258-67-0) is a high-purity analytical reference standard with the molecular formula C16H8ClF6N3O and a molecular weight of 407.70 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 8-Chloro-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 407.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 8-Chloro-6-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H8ClF6N3O |
| Molecular Weight | 407.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-N-(3-chloro-4-(N-(4-chlorophenyl)sulfamoyl)phenyl)propanamide (CAS 749902-82-7)
- 1-Benzyl-5-chloro-N-(3,5-dichlorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 339024-51-0)
- 2-Chloro-N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)benzamide (CAS 338784-47-7)
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- 5-Chloro-1-(2,6-dichlorobenzyl)-6-oxo-N-phenyl-1,6-dihydropyridine-3-carboxamide (CAS 400086-12-6)
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- 5-Chloro-1-(3-chlorobenzyl)-N-(4-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338977-74-5)
- 5-Chloro-1-[(3,4-dichlorophenyl)methyl]-6-oxo-N-phenyl-1,6-dihydropyridine-3-carboxamide (CAS 400086-06-8)
Recommended Standards
- N-(4-chlorophenyl)-2-(N-(2,4-dichlorophenyl)methylsulfonamido)acetamide (CAS 343373-99-9)
- 2,3-Dichloro-N-[(2E)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]benzene-1-sulfonamide (CAS 672951-80-3)
- tert-Butyl (2-((2-bromo-4-chlorobenzo[d]thiazol-6-yl)oxy)ethyl)carbamate (CAS 2173071-64-0)
- 7784-23-8 L903Z8J9VR Aluminum iodide Aluminium iodide Aluminum iodide (AlI3) EINECS 232-054-8 UNII-L903Z8J9VR (CAS 7784-23-8)
- 2-(Hydroxymethyl)-4-methoxy-3-methylbenzonitrile (CAS 1370587-32-8)
- 5-(2-Hydroxypropan-2-yl)-1,3,4-oxadiazol-2(3H)-one (CAS 86354-17-8)
- 3-Difluoromethoxy-5-(trifluoromethyl)benzonitrile (CAS 1806277-95-1)
- 3-(2-(tert-Butoxy)ethoxy)-4-nitrobenzoic acid (CAS 1775687-16-5)
- 2-(Difluoromethoxy)-4-iodobenzo[d]oxazole (CAS 1806425-62-6)
- 4-Chloro-2-nitro-N-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)benzenesulfonamide (CAS 866152-03-6)
- (5-Amino-1-(3-chlorophenyl)-1H-pyrazol-4-yl)(4-chlorophenyl)methanone (CAS 618091-50-2)
- 6-(4-Chlorophenyl)-3-(pyrrolidin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1706451-09-3)
- 2-Chloro-6-methoxy-4-methyl-3-nitropyridine (CAS 2387444-27-9)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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