3-Chloro-6-(2,4-difluorophenoxy)pyridazine CAS 353258-85-2
| CAS No. | 353258-85-2 |
| Molecular Formula | C10H5ClF2N2O |
| Molecular Weight | 242.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-Chloro-6-(2,4-difluorophenoxy)pyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-Chloro-6-(2,4-difluorophenoxy)pyridazine (CAS 353258-85-2) is a high-purity analytical reference standard with the molecular formula C10H5ClF2N2O and a molecular weight of 242.61 g/mol.
The molecular framework of 3-Chloro-6-(2,4-difluorophenoxy)pyridazine (C10H5ClF2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H5ClF2N2O |
| Molecular Weight | 242.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- Tulobuterol Impurity 13 (CAS CATO-C4X-213413)
- 4-(2-Chlorophenoxy)-5,6-difluoropyrimidine (CAS 193741-72-9)
- Methyl 2-{6-chloro-3-oxo-2h,3h-[1,2,4]triazolo[4,3-b]pyridazin-2-yl}acetate (CAS 1394041-52-1)
- 3-(7-Chlorobenzo[d][1,3]dioxol-5-yl)-2-oxopropanoic acid (CAS 1153355-02-2)
- 6-Chloro-2-ethoxynicotinaldehyde (CAS 1884246-82-5)
- (R)-Benzyl 2-methyl-3-oxopiperazine-1-carboxylate (CAS 1373232-19-9)
- 2-(2-Formyl-5-methoxyphenoxy)acetonitrile (CAS 108656-11-7)
- (3aR,4R,6aS)-4-{[(tert-Butyldimethylsilyl)oxy]methyl}-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyrrole (CAS 153172-31-7)
- Empagliflozin Impurity 103 (CAS CATO-C4X-1065103)
- 1-(3-(4-Fluorophenyl)-1H-1,2,4-triazol-5-yl)ethanamine (CAS 1343369-06-1)
- 4,6-Diamino-2-(methylthio)pyrimidine-5-sulfonic acid (CAS 53286-05-8)
- 3-Heptyl-4-hexyl-1H-pyrazol-5(4H)-one (CAS 91990-66-8)
- 2-(4-Nitrophenyl)-4,5-dihydrooxazole (CAS 7465-63-6)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com