3-(2-Oxo-1,3-oxazolidin-3-yl)benzonitrile CAS 353265-77-7
| CAS No. | 353265-77-7 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Oxo-1,3-oxazolidin-3-yl)benzonitrile (CAS 353265-77-7) is a high-purity analytical reference standard with the molecular formula C10H8N2O2 and a molecular weight of 188.18 g/mol.
3-(2-Oxo-1,3-oxazolidin-3-yl)benzonitrile (C10H8N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Oxo Standards
- 4-(2-Oxo-1,3-oxazolidin-3-yl)benzonitrile (CAS 208709-23-3)
- 6-(2-oxo-1,3-oxazolidin-3-yl)pyridine-3-carbonitrile (CAS 1311318-26-9)
- 5-benzyl-1,3-oxazolidin-2-one (CAS 42746-49-6)
- (2-Oxo-1,3-oxazolidin-5-yl)methanesulfonyl chloride (CAS 1593906-79-6)
- 3-(2-oxo-1,3-oxazolidin-3-yl)propanethioamide (CAS 127914-07-2)
- 2-[(2-oxo-1,3-oxazolidin-3-yl)methyl]benzonitrile (CAS 1019120-04-7)
- 4-(2-Oxo-1,3-oxazolidin-3-yl)butanoic acid (CAS 933686-66-9)
- 4-(4-oxo-1,3-oxazolidin-3-yl)butanoic acid (CAS 886502-29-0)
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