4-Benzyl-5-(4-fluorophenyl)-4h-1,2,4-triazole-3-thiol CAS 353287-91-9

Purity 97%+In StockPharmaceutical Standards
CAS No.353287-91-9
Molecular FormulaC15H12FN3S
Molecular Weight285.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Benzyl-5-(4-fluorophenyl)-4h-1,2,4-triazole-3-thiol CAS 353287-91-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Benzyl-5-(4-fluorophenyl)-4h-1,2,4-triazole-3-thiol.

4-Benzyl-5-(4-fluorophenyl)-4h-1,2,4-triazole-3-thiol (CAS 353287-91-9), molecular formula C15H12FN3S and molecular weight 285.34 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Benzyl-5-(4-fluorophenyl)-4h-1,2,4-triazole-3-thiol (C15H12FN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 4-Benzyl-5-(4-fluorophenyl)-4h-1,2,4-triazole-3-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H12FN3S
Molecular Weight285.34 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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