6-Bromo-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)quinoline-4-carboxylic acid CAS 353501-34-5
| CAS No. | 353501-34-5 |
| Molecular Formula | C18H12BrNO4 |
| Molecular Weight | 386.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Bromo-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)quinoline-4-carboxylic acid (CAS 353501-34-5) is a high-purity analytical reference standard with the molecular formula C18H12BrNO4 and a molecular weight of 386.20 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 6-Bromo-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)quinoline-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 386.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12BrNO4 |
| Molecular Weight | 386.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 6-Bromo-4-((4-methyl-3-nitrophenyl)amino)quinoline-3-carbaldehyde (CAS 1431510-26-7)
- 2-Bromo-1-(5-nitro-3,4-diphenylfuran-2-yl)ethanone (CAS 93261-88-2)
- 5-(((4-Bromo-2,5-dimethoxyphenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 133400-93-8)
- 2-Bromo-6-[6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2(1H)-yl]benzaldehyde (CAS 1642290-28-5)
- 3-Bromo-5,7-difluoro-1-tosyl-1H-indole (CAS 1878207-48-7)
- 3-(3-Bromo-4-methoxy-phenylsulfamoyl)-benzoic acid (CAS 568551-62-2)
- 2-Bromo-4-formylphenyl 4-nitrobenzenesulfonate (CAS 1432437-84-7)
- 2-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-6-cyclopropoxy-4-(trifluoromethyl)benzonitrile (CAS 2629317-41-3)
Recommended Standards
- 4-Amino-5-(4-bromobenzoyl)-N-phenylisoxazole-3-carboxamide (CAS 830326-87-9)
- 8-(3-Bromophenyl)-5,12,14-trioxa-2-azatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),3(7),10,15-tetraen-6-one (CAS 867068-21-1)
- 3,5-Dichloro-N-(prop-2-yn-1-yl)-N-(3-(trifluoromethyl)benzyl)benzamide (CAS 400075-25-4)
- 9-(2-Bromophenyl)-6,9-dihydro-[1,3]dioxolo[4,5-g]furo[3,4-b]quinolin-8(5H)-one (CAS 866138-52-5)
- 2-(4-Nitrophenyl)-N-(prop-2-yn-1-yl)acetamide (CAS 1089619-78-2)
- 4-Benzyl-5-((o-tolyloxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 346641-16-5)
- Theobromine Sodium Salicylate (CAS 8048-31-5)
- (5E)-3-Ethyl-5-[(4-methoxy-3-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 301193-97-5)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-cyclopropylbutanoic acid (CAS 2350690-47-8)
- Ethyl 2-fluoro-4-(2-hydroxypyrimidin-5-yl)benzoate (CAS 1111104-20-1)
- 2-(2-(Heptan-2-ylamino)ethoxy)ethan-1-ol (CAS 1042523-06-7)
- Bis(cyclopentadienyl)vanadium bromide (CAS 64815-29-8)
- [3-(1H-Indol-1-yl)propyl]amine methanesulfonate (CAS 1185693-68-8)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com