1-Methyl-[1,2,4]triazolo[4,3-a]quinoline CAS 35359-22-9
| CAS No. | 35359-22-9 |
| Molecular Formula | C11H9N3 |
| Molecular Weight | 183.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Methyl-[1,2,4]triazolo[4,3-a]quinoline (CAS 35359-22-9), molecular formula C11H9N3 and molecular weight 183.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methyl-[1,2,4]triazolo[4,3-a]quinoline (C11H9N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9N3 |
| Molecular Weight | 183.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 3-Methyl-[1,2,4]triazolo[3,4-a]isoquinoline (CAS 7639-56-7)
- 5-Methyl-[1,2,4]triazolo[4,3-a]quinoline (CAS 35359-25-2)
- 3-Propyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-amine (CAS 217788-67-5)
- 4-Methyl-[1,2,3]triazolo[1,5-a]quinoxaline (CAS 111339-68-5)
- 4-Methyl-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 19848-84-1)
- 3-methyl-[1,2,4]triazolo[3,4-a]phthalazine (CAS 20062-41-3)
- 3-([1,2,4]triazolo[4,3-a]pyridin-3-yl)propan-1-amine (CAS 610276-38-5)
- [1,2,3]Triazolo[1,5-a]pyridine-3-carbonyl chloride (CAS 87838-57-1)
Recommended Standards
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