5-[(4-chlorophenyl)methyl]-1,3-thiazol-2-amine hydrochloride CAS 353745-15-0
| CAS No. | 353745-15-0 |
| Molecular Formula | C10H9ClN2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-[(4-chlorophenyl)methyl]-1,3-thiazol-2-amine hydrochloride (CAS 353745-15-0), molecular formula C10H9ClN2SHCl and molecular weight 261.16 g/mol, is a CATO reference standard with documented purity and traceability.
5-[(4-chlorophenyl)methyl]-1,3-thiazol-2-amine hydrochloride (C10H9ClN2SHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-[(4-chlorophenyl)methyl]-1,3-thiazol-2-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2S HCl |
| Molecular Weight | 261.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chlorophenyl Standards
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- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
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- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
- N1-Isopropyl-N4-(1,3,4-thiadiazol-2-yl)succinamide (CAS 107811-27-8)
- 4-(4-Bromobenzyloxy)oxane (CAS 215453-86-4)
- (S,R,S)-AHPC-acetamido-O-PEG5-C2-amine HCl (CAS 2086298-72-6)
- 6-Methyl-4-(pyrrolidin-1-yl)pyridin-2(1H)-one (CAS 62034-96-2)
- 2-(4-methoxynaphthalen-1-yl)ethan-1-amine (CAS 910396-31-5)
- (S)-2-(4-benzylmorpholin-3-yl)ethan-1-ol (CAS 2165558-40-5)
- tert-Butyl 4-carbamimidoylpiperidine-1-carboxylate (CAS 885270-23-5)
- 4,4'-((1E,1'E)-[1,1'-Biphenyl]-4,4'-diylbis(ethene-2,1-diyl))bis(N,N-diphenylaniline) (CAS 523977-57-3)
- 18α-Glycyrrhizic Acid Ammonium Salt (CAS 80287-34-9)
- Peptide YY (13-36) (canine, mouse, porcine, rat) (CAS 86895-09-2)
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