2,2-Difluoro-1-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethanone CAS 353780-07-1
| CAS No. | 353780-07-1 |
| Molecular Formula | C9H14F2N2O |
| Molecular Weight | 204.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,2-Difluoro-1-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethanone (CAS 353780-07-1), molecular formula C9H14F2N2O and molecular weight 204.22 g/mol, is a CATO reference standard with documented purity and traceability.
2,2-Difluoro-1-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethanone (C9H14F2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2,2-Difluoro-1-(hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H14F2N2O |
| Molecular Weight | 204.22 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 3',4-Difluoro-2-methylbiphenyl (CAS 1214341-12-4)
- 2,4-Difluoro-4'-methyl-1,1'-biphenyl (CAS 1358983-25-1)
- 2,2-Difluoro-1-(1-Piperazinyl)-4-Penten-1-One (CAS 191351-84-5)
- 3,5-Difluoro-4'-methyl-1,1'-biphenyl (CAS 97067-20-4)
- 4,4-Difluoro-1-phenyl-1,3-butanedione 3-benzoyl-1,1-difluoroacetone 4,4-difluoro-1-phenylbutane-1,3-dione 62679-61-2 (CAS 62679-61-2)
- 3,5-Difluoro-2-propoxybenzenethiol (CAS 1379317-09-5)
- (3,4-Difluoro-5-methoxyphenyl)(ethyl)sulfane (CAS 1379324-74-9)
- 3,4-Difluoro-5-propoxybenzenethiol (CAS 1379342-91-2)
Recommended Standards
- 2,2,5,5-Tetrakis(hydroxymethyl)cyclopentan-1-one (CAS 3322-70-1)
- 2,2-Dimethyl-2H-chromene-6-carboxylic acid (CAS 34818-56-9)
- 2-(5-Ethylbenzofuran-3-yl)acetic acid (CAS 882248-24-0)
- 2,3-Dihydrospiro[indene-1,2'-[1,3]dioxolane]-4-carbaldehyde (CAS 954238-31-4)
- 3,4,5-Trimethylaniline hydrochloride (CAS 90642-55-0)
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-bromobenzoic acid (CAS 2243504-14-3)
- 5,10,15,20-Tetra(pyridin-3-yl)porphyrin (CAS 40882-83-5)
- Tin(II) acetylacetonate (CAS 16009-86-2)
- (αR)-α-(Iodomethyl)-3,4-dimethoxybenzenemethanol (CAS 833353-17-6)
- 2’-Hydroxy-4’-(trifluoromethyl)acetophenone (CAS 228572-69-8)
- 1-(4-Methoxybenzyl)-2-oxo-N-(3,4,5-trimethoxyphenyl)-1,2-dihydropyridine-3-carboxamide (CAS 400077-78-3)
- Phenyl 5-nitropyridin-2-ylcarbamate (CAS 1173460-00-8)
- 3-Chloro-5-(trifluoromethyl)-2-[3-(trifluoromethyl)phenoxy]pyridine (CAS 1795483-74-7)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com