3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol CAS 354-68-7
| CAS No. | 354-68-7 |
| Molecular Formula | C4H8F3NO |
| Molecular Weight | 143.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol (CAS 354-68-7) is a high-purity analytical reference standard with the molecular formula C4H8F3NO and a molecular weight of 143.11 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H8F3NO |
| Molecular Weight | 143.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
- (S)-2-amino-4,4,4-trifluorobutan-1-ol (CAS 1268883-23-3)
- 3-Amino-1,1,1-trifluorobutan-2-ol (CAS 129681-16-9)
- (S)-3-Amino-1,1,1-trifluoro-2-methylpropan-2-ol (CAS 1334547-38-4)
- (R)-2-Amino-3,3,3-trifluoro-2-methylpropan-1-ol (CAS 1352874-89-5)
- (S)-3-Amino-4,4,4-trifluoro-1-butanol (CAS 1388098-52-9)
- (R)-2-amino-4,4,4-trifluorobutan-1-ol (CAS 1388797-83-8)
- (S)-2-Amino-3,3,3-trifluoro-2-methylpropan-1-ol (CAS 1390706-29-2)
- 3-amino-4,4,4-trifluorobutan-2-ol (CAS 1391251-53-8)
Recommended Standards
- 2-amino-4,4,4-trifluoro-butan-1-ol (CAS 497165-91-0)
- 3-Amino-4,4,4-trifluorobutan-1-ol (CAS 914223-46-4)
- 2-(2,2,2-trifluoroethylamino)ethanol (CAS 371-99-3)
- 4-Amino-2-hydroxy-1,1,1-trifluorobutane (CAS 57165-84-1)
- 12H-Benzo[b]phenoxazine (CAS 258-04-8)
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- 12-Oxa-2,6,10-triazatridecanoic acid, 6-(carboxymethyl)-13-(9H-fluoren-9-yl)-11-oxo-, 1-(9H-fluoren-9-ylmethyl) ester, potassium salt, sulfate (CAS 346694-76-6)
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