3-(3-Bromo-4-ethoxy-5-methoxyphenyl)acrylic acid CAS 354531-46-7
| CAS No. | 354531-46-7 |
| Molecular Formula | C12H13BrO4 |
| Molecular Weight | 301.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(3-Bromo-4-ethoxy-5-methoxyphenyl)acrylic acid (CAS 354531-46-7) is a high-purity analytical reference standard with the molecular formula C12H13BrO4 and a molecular weight of 301.13 g/mol.
The molecular framework of 3-(3-Bromo-4-ethoxy-5-methoxyphenyl)acrylic acid (C12H13BrO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 3-(3-Bromo-4-ethoxy-5-methoxyphenyl)acrylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13BrO4 |
| Molecular Weight | 301.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
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Recommended Standards
- 3-(3,5-Dichlorophenyl)-1-propionylimidazolidine-2,4-dione (CAS 32955-84-3)
- 3-(3-Bromo-5-ethoxy-4-methoxyphenyl)acrylic acid (CAS 423736-20-3)
- 3-(2-Bromo-5-ethoxy-4-methoxyphenyl)acrylic acid (CAS 423747-21-1)
- 3-(3'-Bromophenyl)coumarin (CAS 720673-87-0)
- 4-Amino-5-methylhexanoic acid (CAS 74924-02-0)
- 5-(Hydroxymethyl)-3-methylpyrrolidin-2-one (CAS 138078-58-7)
- (E)-Methyl 4-(2-(3-ethoxy-2,2-difluoro-3-oxo-1-(2-((2-(trifluoromethyl)phenyl)sulfonyl)hydrazono)propyl)-4-methylphenoxy)butanoate (CAS 2738683-68-4)
- 2-Bromo-1-(1,5-dimethyl-1H-pyrazol-3-yl)ethanone (CAS 1420981-12-9)
- Ezetimibe Impurity 49 (CAS 1044664-24-5)
- 2-(Difluoromethyl)-3,5-dihydroxypyridine-6-carboxaldehyde (CAS 1804698-20-1)
- Ethyl 1-(5-chloro-6-oxo-1,6-dihydro-4-pyridazinyl)-4-piperidinecarboxylate (CAS 952183-76-5)
- 2-Oxiranenonanoic acid,methyl ester (CAS 22663-09-8)
- 6-Bromo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-4-ol (CAS 2763397-13-1)
- Semaglutide-d15 (CAS 910463-68-2(non-labelled))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com