4-((4-Bromo-2-fluorophenyl)amino)-4-oxobutanoic acid CAS 354545-86-1
| CAS No. | 354545-86-1 |
| Molecular Formula | C10H9BrFNO3 |
| Molecular Weight | 290.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-((4-Bromo-2-fluorophenyl)amino)-4-oxobutanoic acid (CAS 354545-86-1), molecular formula C10H9BrFNO3 and molecular weight 290.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-((4-Bromo-2-fluorophenyl)amino)-4-oxobutanoic acid (C10H9BrFNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9BrFNO3 |
| Molecular Weight | 290.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-[2-(Benzyloxy)ethoxy]-5-fluorophenylboronic acid (CAS 2377606-07-8)
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- tert-Butyldiisopropylphosphine (CAS 51567-05-6)
- 2-Chloro-5-(1-methylcyclobutyl)pyridine (CAS 1935325-79-3)
- 2-{[5-(4-tert-butylphenyl)-4-ethyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide (CAS 893726-82-4)
- tert-butyl 2-(cyanomethyl)azetidine-1-carboxylate (CAS 1824110-25-9)
- {5-bromo-2-[methyl(2,2,2-trifluoroethyl)amino]pyridin-3-yl}methanol (CAS 1250558-07-6)
- N-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazole-5-sulfonamide (CAS 69190-99-4)
- 2-((2-(8-Bromo-3-methyl-2,6-dioxo-1,2,3,6-tetrahydro-7h-purin-7-yl)ethyl)thio)-N-phenylacetamide (CAS 476481-78-4)
- tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate (CAS 927652-04-8)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
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