6-(Tert-butyl)-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile CAS 354556-52-8
| CAS No. | 354556-52-8 |
| Molecular Formula | C27H28N2O2S2 |
| Molecular Weight | 476.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 476.65 g/mol gives 6-(Tert-butyl)-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-(Tert-butyl)-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 354556-52-8), molecular formula C27H28N2O2S2 and molecular weight 476.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-(Tert-butyl)-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (C27H28N2O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-(Tert-butyl)-2-((2-(3-methoxyphenyl)-2-oxoethyl)thio)-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H28N2O2S2 |
| Molecular Weight | 476.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Recommended Standards
- 2,6-Bis(trimethylsilyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine 4-oxide (CAS 2416166-99-7)
- N-(2-Methoxy-5-methylphenyl)-2-{[4-({[(2-methoxy-5-methylphenyl)carbamoyl]methyl}sulfanyl)butyl]sulfanyl}acetamide (CAS 301194-33-2)
- 16-((Anthracene-9-carbonyl)oxy)hexadecanoic acid (CAS 64821-29-0)
- Menaquinone impurity 21 (CAS CATO-C4X-207621)
- 3-[2-(4-Chloroanilino)-1-nitrovinyl]-2-benzofuran-1(3H)-one (CAS 338753-94-9)
- (3R)-3-methylpyrrolidin-3-ol (CAS 392338-65-7)
- 5-(Chloromethyl)-n-(4-ethylphenyl)-1,3,4-thiadiazole-2-carboxamide (CAS 1087792-49-1)
- 1,6-Dimethyl-4-oxo-1,4-dihydropyridine-3-carbonitrile (CAS 1706451-89-9)
- (2E)-1-(2-Chlorophenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one (CAS 1354942-29-2)
- 4-(Furan-2-yl)phenol (CAS 35461-94-0)
- (4r)-7,8-Dimethyl-3,4-dihydro-2h-1-benzopyran-4-amine hydrochloride (CAS 730980-50-4)
- 2-Methyl-5-oxo-4-(thiophen-2-yl)-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 691868-99-2)
- Umeclidinium Impurity 7 (CAS CATO-C4X-13397)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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