4-(3-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acid CAS 354812-80-9
| CAS No. | 354812-80-9 |
| Molecular Formula | C19H16BrNO2 |
| Molecular Weight | 370.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acid.
CATO supplies 4-(3-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acid (CAS 354812-80-9), a certified reference material (molecular formula C19H16BrNO2, MW 370.24 g/mol) for analytical method development and quality control.
4-(3-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-6-carboxylic acid (C19H16BrNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H16BrNO2 |
| Molecular Weight | 370.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2-Bromo-2,2-dimethyl-acetamido-PEG3-acid (CAS 2279944-67-9)
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- 2-(tert-Butyl)-4-(cyclohexyloxy)phenol (CAS 1243279-31-3)
- 1,2,4-Thiadiazolidine-3,5-dithione (CAS 20939-17-7)
- 2-[(1E)-{[(2H-1,3-benzodioxol-5-yl)methyl]imino}methyl]-6-bromo-4-methoxyphenol (CAS 477848-16-1)
- (5S)-5H,6H,7H-cyclopenta[b]pyridin-5-ol (CAS 1443112-10-4)
- (S)-6-Bromo-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1213547-18-2)
- [2,2'-Bipyridine]-4,4'-diyldiphosphonic acid (CAS 194800-56-1)
- Europium 2,4-pentanedionate (CAS 14284-86-7)
- Naratriptan 2-Carboxylic Acid (CAS 874583-40-1)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
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